2025 Atlantic Coast Conference Leaders Passes Defended - Games in November Only through 11/22/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Miami (FL) | 4 | 4 | 20 | 24 | 6.00 |
| 2 | Virginia | 3 | 2 | 20 | 22 | 7.33 |
| 2 | California | 3 | 1 | 21 | 22 | 7.33 |
| 4 | Pittsburgh | 3 | 7 | 13 | 20 | 6.67 |
| 5 | Clemson | 4 | 2 | 17 | 19 | 4.75 |
| 6 | Wake Forest | 4 | 0 | 17 | 17 | 4.25 |
| 7 | Stanford | 3 | 2 | 14 | 16 | 5.33 |
| 8 | SMU | 3 | 5 | 9 | 14 | 4.67 |
| 9 | NC State | 3 | 3 | 10 | 13 | 4.33 |
| 10 | Duke | 4 | 2 | 10 | 12 | 3.00 |
| 11 | North Carolina | 3 | 1 | 10 | 11 | 3.67 |
| 11 | Louisville | 4 | 0 | 11 | 11 | 2.75 |
| 13 | Boston College | 3 | 1 | 9 | 10 | 3.33 |
| 13 | Florida State | 4 | 2 | 8 | 10 | 2.50 |
| 15 | Syracuse | 2 | 0 | 6 | 6 | 3.00 |
| 15 | Virginia Tech | 3 | 1 | 5 | 6 | 2.00 |
| 15 | Georgia Tech | 3 | 0 | 6 | 6 | 2.00 |