2025 Atlantic Coast Conference Leaders Passes Defended - Games Lost Only through 11/22/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Boston College | 10 | 5 | 29 | 34 | 3.40 |
| 2 | Clemson | 5 | 1 | 27 | 28 | 5.60 |
| 3 | North Carolina | 7 | 2 | 22 | 24 | 3.43 |
| 4 | SMU | 3 | 3 | 19 | 22 | 7.33 |
| 4 | NC State | 5 | 2 | 20 | 22 | 4.40 |
| 6 | California | 5 | 1 | 19 | 20 | 4.00 |
| 7 | Virginia Tech | 8 | 3 | 16 | 19 | 2.38 |
| 8 | Duke | 5 | 2 | 16 | 18 | 3.60 |
| 8 | Stanford | 7 | 2 | 16 | 18 | 2.57 |
| 8 | Syracuse | 8 | 2 | 16 | 18 | 2.25 |
| 11 | Florida State | 6 | 6 | 10 | 16 | 2.67 |
| 12 | Pittsburgh | 3 | 5 | 10 | 15 | 5.00 |
| 13 | Miami (FL) | 2 | 0 | 12 | 12 | 6.00 |
| 14 | Louisville | 4 | 0 | 11 | 11 | 2.75 |
| 15 | Virginia | 2 | 0 | 10 | 10 | 5.00 |
| 15 | Wake Forest | 3 | 0 | 10 | 10 | 3.33 |
| 17 | Georgia Tech | 2 | 0 | 3 | 3 | 1.50 |