2025 Atlantic Coast Conference Leaders Passes Defended - Games Lost Only through 11/01/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Clemson | 5 | 1 | 27 | 28 | 5.60 |
| 2 | Boston College | 8 | 4 | 22 | 26 | 3.25 |
| 3 | SMU | 3 | 3 | 19 | 22 | 7.33 |
| 4 | NC State | 4 | 2 | 18 | 20 | 5.00 |
| 5 | California | 4 | 1 | 16 | 17 | 4.25 |
| 5 | Stanford | 6 | 2 | 15 | 17 | 2.83 |
| 7 | North Carolina | 5 | 2 | 14 | 16 | 3.20 |
| 7 | Virginia Tech | 6 | 3 | 13 | 16 | 2.67 |
| 9 | Florida State | 4 | 6 | 7 | 13 | 3.25 |
| 10 | Miami (FL) | 2 | 0 | 12 | 12 | 6.00 |
| 10 | Syracuse | 6 | 2 | 10 | 12 | 2.00 |
| 12 | Wake Forest | 3 | 0 | 10 | 10 | 3.33 |
| 13 | Pittsburgh | 2 | 3 | 6 | 9 | 4.50 |
| 13 | Duke | 3 | 0 | 9 | 9 | 3.00 |
| 15 | Virginia | 1 | 0 | 3 | 3 | 3.00 |
| 16 | Louisville | 1 | 0 | 2 | 2 | 2.00 |
| 17 | Georgia Tech | 1 | 0 | 1 | 1 | 1.00 |