2025 Atlantic Coast Conference Leaders Passes Defended - Games vs. Unranked Teams Only (AP Poll) through 12/20/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Virginia | 13 | 13 | 59 | 72 | 5.54 |
| 2 | SMU | 11 | 15 | 56 | 71 | 6.45 |
| 3 | Clemson | 11 | 9 | 60 | 69 | 6.27 |
| 4 | Miami (FL) | 11 | 11 | 43 | 54 | 4.91 |
| 5 | California | 11 | 8 | 45 | 53 | 4.82 |
| 6 | Wake Forest | 10 | 4 | 46 | 50 | 5.00 |
| 7 | NC State | 9 | 6 | 40 | 46 | 5.11 |
| 8 | Louisville | 9 | 9 | 33 | 42 | 4.67 |
| 9 | Stanford | 8 | 3 | 38 | 41 | 5.13 |
| 10 | Pittsburgh | 9 | 10 | 30 | 40 | 4.44 |
| 10 | North Carolina | 11 | 5 | 35 | 40 | 3.64 |
| 12 | Boston College | 10 | 6 | 33 | 39 | 3.90 |
| 13 | Syracuse | 9 | 5 | 32 | 37 | 4.11 |
| 14 | Duke | 9 | 9 | 25 | 34 | 3.78 |
| 15 | Georgia Tech | 11 | 2 | 30 | 32 | 2.91 |
| 16 | Virginia Tech | 8 | 3 | 21 | 24 | 3.00 |
| 16 | Florida State | 9 | 9 | 15 | 24 | 2.67 |