2025 Atlantic Coast Conference Leaders Passes Defended - Games vs. FBS non-Power 5 Conference Teams Only through 11/22/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Miami (FL) | 2 | 2 | 10 | 12 | 6.00 |
| 2 | Virginia | 1 | 1 | 9 | 10 | 10.00 |
| 2 | Louisville | 2 | 3 | 7 | 10 | 5.00 |
| 2 | Syracuse | 2 | 0 | 10 | 10 | 5.00 |
| 2 | Wake Forest | 2 | 0 | 10 | 10 | 5.00 |
| 6 | Stanford | 2 | 0 | 9 | 9 | 4.50 |
| 7 | Pittsburgh | 2 | 2 | 6 | 8 | 4.00 |
| 7 | NC State | 2 | 1 | 7 | 8 | 4.00 |
| 9 | North Carolina | 1 | 2 | 5 | 7 | 7.00 |
| 10 | Clemson | 1 | 3 | 3 | 6 | 6.00 |
| 10 | SMU | 1 | 3 | 3 | 6 | 6.00 |
| 10 | Duke | 2 | 0 | 6 | 6 | 3.00 |
| 13 | Georgia Tech | 1 | 0 | 5 | 5 | 5.00 |
| 13 | Boston College | 2 | 0 | 5 | 5 | 2.50 |
| 15 | California | 1 | 0 | 3 | 3 | 3.00 |
| 16 | Florida State | 1 | 1 | 1 | 2 | 2.00 |
| 16 | Virginia Tech | 1 | 0 | 2 | 2 | 2.00 |