2025 Atlantic Coast Conference Leaders Passes Defended - Games vs. Non-Conference Teams Only through 09/19/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | SMU | 3 | 5 | 18 | 23 | 7.67 |
| 2 | Syracuse | 3 | 2 | 18 | 20 | 6.67 |
| 3 | California | 3 | 3 | 15 | 18 | 6.00 |
| 4 | North Carolina | 3 | 4 | 10 | 14 | 4.67 |
| 5 | Miami (FL) | 3 | 3 | 10 | 13 | 4.33 |
| 6 | Virginia | 2 | 1 | 11 | 12 | 6.00 |
| 6 | Wake Forest | 2 | 1 | 11 | 12 | 6.00 |
| 8 | Clemson | 2 | 3 | 8 | 11 | 5.50 |
| 9 | Pittsburgh | 3 | 2 | 8 | 10 | 3.33 |
| 10 | Florida State | 2 | 2 | 7 | 9 | 4.50 |
| 10 | Boston College | 2 | 1 | 8 | 9 | 4.50 |
| 12 | Louisville | 2 | 1 | 6 | 7 | 3.50 |
| 12 | Virginia Tech | 3 | 1 | 6 | 7 | 2.33 |
| 14 | Duke | 3 | 0 | 6 | 6 | 2.00 |
| 15 | Georgia Tech | 2 | 0 | 4 | 4 | 2.00 |
| 16 | NC State | 1 | 0 | 3 | 3 | 3.00 |
| 17 | Stanford | 2 | 0 | 1 | 1 | 0.50 |