2025 Atlantic Coast Conference Leaders Passes Defended - Games vs. Non-Conference Teams Only through 11/22/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | SMU | 4 | 6 | 25 | 31 | 7.75 |
| 2 | Syracuse | 4 | 2 | 21 | 23 | 5.75 |
| 3 | Wake Forest | 4 | 2 | 20 | 22 | 5.50 |
| 4 | California | 4 | 3 | 18 | 21 | 5.25 |
| 5 | Virginia | 3 | 3 | 17 | 20 | 6.67 |
| 6 | Clemson | 3 | 4 | 13 | 17 | 5.67 |
| 7 | Pittsburgh | 4 | 4 | 12 | 16 | 4.00 |
| 8 | North Carolina | 4 | 4 | 11 | 15 | 3.75 |
| 9 | Boston College | 4 | 1 | 13 | 14 | 3.50 |
| 10 | Louisville | 3 | 3 | 10 | 13 | 4.33 |
| 10 | Miami (FL) | 4 | 3 | 10 | 13 | 3.25 |
| 12 | Florida State | 3 | 3 | 8 | 11 | 3.67 |
| 12 | NC State | 3 | 1 | 10 | 11 | 3.67 |
| 12 | Virginia Tech | 4 | 2 | 9 | 11 | 2.75 |
| 12 | Duke | 4 | 0 | 11 | 11 | 2.75 |
| 16 | Georgia Tech | 3 | 0 | 9 | 9 | 3.00 |
| 16 | Stanford | 3 | 0 | 9 | 9 | 3.00 |