2025 Atlantic Coast Conference Leaders Passes Defended - Games vs. Conference Teams Only through 11/01/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | SMU | 5 | 8 | 28 | 36 | 7.20 |
| 2 | Louisville | 5 | 9 | 21 | 30 | 6.00 |
| 2 | Pittsburgh | 6 | 8 | 22 | 30 | 5.00 |
| 2 | Virginia | 6 | 7 | 23 | 30 | 5.00 |
| 2 | Clemson | 6 | 2 | 28 | 30 | 5.00 |
| 6 | California | 5 | 3 | 26 | 29 | 5.80 |
| 7 | Stanford | 6 | 3 | 25 | 28 | 4.67 |
| 8 | Miami (FL) | 4 | 4 | 21 | 25 | 6.25 |
| 8 | NC State | 6 | 5 | 20 | 25 | 4.17 |
| 10 | Duke | 5 | 8 | 14 | 22 | 4.40 |
| 11 | Wake Forest | 5 | 2 | 19 | 21 | 4.20 |
| 12 | Boston College | 5 | 4 | 16 | 20 | 4.00 |
| 13 | Georgia Tech | 6 | 2 | 16 | 18 | 3.00 |
| 14 | Virginia Tech | 5 | 2 | 15 | 17 | 3.40 |
| 15 | Florida State | 5 | 7 | 9 | 16 | 3.20 |
| 16 | North Carolina | 4 | 1 | 14 | 15 | 3.75 |
| 17 | Syracuse | 6 | 3 | 11 | 14 | 2.33 |