2025 Atlantic Coast Conference Leaders Passes Defended - Games vs. Conference Teams Only through 12/20/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Virginia | 10 | 10 | 42 | 52 | 5.20 |
| 2 | SMU | 8 | 11 | 35 | 46 | 5.75 |
| 3 | Miami (FL) | 8 | 9 | 36 | 45 | 5.63 |
| 4 | California | 8 | 5 | 38 | 43 | 5.38 |
| 5 | NC State | 9 | 7 | 35 | 42 | 4.67 |
| 6 | Duke | 9 | 13 | 28 | 41 | 4.56 |
| 7 | Louisville | 8 | 9 | 30 | 39 | 4.88 |
| 7 | Clemson | 8 | 3 | 36 | 39 | 4.88 |
| 9 | Pittsburgh | 8 | 11 | 27 | 38 | 4.75 |
| 10 | Stanford | 8 | 3 | 33 | 36 | 4.50 |
| 11 | Wake Forest | 8 | 2 | 32 | 34 | 4.25 |
| 12 | North Carolina | 8 | 2 | 27 | 29 | 3.63 |
| 13 | Boston College | 8 | 5 | 23 | 28 | 3.50 |
| 14 | Virginia Tech | 8 | 2 | 23 | 25 | 3.13 |
| 15 | Florida State | 8 | 8 | 15 | 23 | 2.88 |
| 15 | Georgia Tech | 8 | 2 | 21 | 23 | 2.88 |
| 17 | Syracuse | 8 | 3 | 18 | 21 | 2.63 |