2025 Atlantic Coast Conference Leaders Passes Defended - Games at Home Only through 11/22/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Clemson | 7 | 6 | 40 | 46 | 6.57 |
| 2 | SMU | 6 | 9 | 34 | 43 | 7.17 |
| 3 | Miami (FL) | 8 | 9 | 30 | 39 | 4.88 |
| 4 | Stanford | 5 | 3 | 32 | 35 | 7.00 |
| 4 | California | 5 | 2 | 33 | 35 | 7.00 |
| 4 | Wake Forest | 7 | 2 | 33 | 35 | 5.00 |
| 7 | Virginia | 6 | 5 | 29 | 34 | 5.67 |
| 8 | Boston College | 7 | 5 | 25 | 30 | 4.29 |
| 8 | Louisville | 7 | 5 | 25 | 30 | 4.29 |
| 10 | NC State | 6 | 4 | 22 | 26 | 4.33 |
| 10 | Pittsburgh | 6 | 4 | 22 | 26 | 4.33 |
| 12 | North Carolina | 6 | 4 | 21 | 25 | 4.17 |
| 13 | Virginia Tech | 7 | 4 | 20 | 24 | 3.43 |
| 14 | Florida State | 7 | 7 | 15 | 22 | 3.14 |
| 15 | Syracuse | 5 | 3 | 17 | 20 | 4.00 |
| 16 | Duke | 5 | 5 | 13 | 18 | 3.60 |
| 16 | Georgia Tech | 6 | 2 | 16 | 18 | 3.00 |