2025 Atlantic Coast Conference Leaders Passes Defended - Games vs. Conference Teams Only through 11/22/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Virginia | 8 | 7 | 38 | 45 | 5.63 |
| 2 | California | 7 | 4 | 36 | 40 | 5.71 |
| 2 | Clemson | 8 | 3 | 36 | 39 | 4.88 |
| 4 | Miami (FL) | 7 | 8 | 34 | 42 | 6.00 |
| 5 | SMU | 7 | 11 | 33 | 44 | 6.29 |
| 5 | Stanford | 8 | 3 | 33 | 36 | 4.50 |
| 7 | Louisville | 8 | 9 | 30 | 39 | 4.88 |
| 8 | NC State | 8 | 7 | 29 | 36 | 4.50 |
| 9 | Wake Forest | 7 | 2 | 28 | 30 | 4.29 |
| 10 | Pittsburgh | 7 | 10 | 25 | 35 | 5.00 |
| 11 | North Carolina | 7 | 2 | 24 | 26 | 3.71 |
| 12 | Boston College | 7 | 5 | 23 | 28 | 4.00 |
| 13 | Georgia Tech | 8 | 2 | 21 | 23 | 2.88 |
| 14 | Virginia Tech | 7 | 2 | 18 | 20 | 2.86 |
| 15 | Duke | 7 | 10 | 17 | 27 | 3.86 |
| 16 | Florida State | 8 | 8 | 15 | 23 | 2.88 |
| 17 | Syracuse | 7 | 3 | 14 | 17 | 2.43 |