2025 Conference USA Leaders Passes Defended - Games vs. FBS non-Power 5 Conference Teams Only through 09/06/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Sam Houston State | 3 | 2 | 13 | 15 | 5.00 |
| 2 | New Mexico State | 1 | 2 | 6 | 8 | 8.00 |
| 2 | Western Kentucky | 2 | 2 | 6 | 8 | 4.00 |
| 4 | Jacksonville State | 1 | 1 | 5 | 6 | 6.00 |
| 4 | Missouri State | 1 | 1 | 5 | 6 | 6.00 |
| 6 | UTEP | 1 | 0 | 4 | 4 | 4.00 |
| 7 | Liberty | 1 | 0 | 1 | 1 | 1.00 |