2025 Conference USA Leaders Passes Defended - Games Lost Only through 11/01/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | UTEP | 6 | 3 | 24 | 27 | 4.50 |
| 2 | Middle Tennessee State | 7 | 2 | 22 | 24 | 3.43 |
| 3 | FIU | 5 | 1 | 21 | 22 | 4.40 |
| 4 | New Mexico State | 5 | 6 | 18 | 24 | 4.80 |
| 4 | Sam Houston State | 8 | 4 | 18 | 22 | 2.75 |
| 6 | Louisiana Tech | 3 | 2 | 12 | 14 | 4.67 |
| 7 | Liberty | 4 | 2 | 11 | 13 | 3.25 |
| 8 | Missouri State | 3 | 1 | 9 | 10 | 3.33 |
| 9 | Jacksonville State | 3 | 0 | 8 | 8 | 2.67 |
| 10 | Delaware | 4 | 0 | 6 | 6 | 1.50 |
| 11 | Kennesaw State | 2 | 0 | 5 | 5 | 2.50 |
| 12 | Western Kentucky | 2 | 1 | 4 | 5 | 2.50 |