2025 Conference USA Leaders Passes Defended - Games vs. FBS non-Power 5 Conference Teams Only through 01/02/2026
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 10 | 19 | 55 | 74 | 7.40 |
| 2 | FIU | 11 | 12 | 44 | 56 | 5.09 |
| 2 | New Mexico State | 10 | 12 | 43 | 55 | 5.50 |
| 2 | Jacksonville State | 12 | 12 | 43 | 55 | 4.58 |
| 5 | Delaware | 10 | 10 | 29 | 39 | 3.90 |
| 6 | Kennesaw State | 11 | 9 | 45 | 54 | 4.91 |
| 6 | Middle Tennessee State | 10 | 9 | 37 | 46 | 4.60 |
| 8 | Western Kentucky | 11 | 8 | 49 | 57 | 5.18 |
| 9 | Missouri State | 10 | 6 | 47 | 53 | 5.30 |
| 9 | Liberty | 11 | 6 | 36 | 42 | 3.82 |
| 9 | Sam Houston State | 10 | 6 | 26 | 32 | 3.20 |
| 12 | UTEP | 10 | 4 | 32 | 36 | 3.60 |