2025 Conference USA Leaders Passes Defended - Games vs. Non-Conference Teams Only through 11/22/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 4 | 4 | 20 | 24 | 6.00 |
| 2 | Western Kentucky | 4 | 4 | 16 | 20 | 5.00 |
| 2 | Kennesaw State | 4 | 0 | 16 | 16 | 4.00 |
| 4 | FIU | 4 | 3 | 15 | 18 | 4.50 |
| 5 | Sam Houston State | 4 | 4 | 13 | 17 | 4.25 |
| 6 | New Mexico State | 4 | 5 | 12 | 17 | 4.25 |
| 6 | Liberty | 4 | 3 | 12 | 15 | 3.75 |
| 6 | Missouri State | 4 | 3 | 12 | 15 | 3.75 |
| 6 | Jacksonville State | 4 | 2 | 12 | 14 | 3.50 |
| 6 | UTEP | 4 | 1 | 12 | 13 | 3.25 |
| 11 | Delaware | 4 | 4 | 10 | 14 | 3.50 |
| 11 | Middle Tennessee State | 4 | 3 | 10 | 13 | 3.25 |