2025 Conference USA Leaders Passes Defended - Games vs. Conference Teams Only through 12/13/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 8 | 16 | 43 | 59 | 7.38 |
| 2 | New Mexico State | 8 | 10 | 36 | 46 | 5.75 |
| 2 | FIU | 8 | 9 | 36 | 45 | 5.63 |
| 2 | Kennesaw State | 9 | 8 | 36 | 44 | 4.89 |
| 2 | Missouri State | 8 | 5 | 36 | 41 | 5.13 |
| 2 | Western Kentucky | 8 | 4 | 36 | 40 | 5.00 |
| 7 | Jacksonville State | 9 | 10 | 32 | 42 | 4.67 |
| 8 | Middle Tennessee State | 8 | 7 | 31 | 38 | 4.75 |
| 9 | Liberty | 8 | 4 | 26 | 30 | 3.75 |
| 9 | UTEP | 8 | 4 | 26 | 30 | 3.75 |
| 11 | Delaware | 8 | 9 | 22 | 31 | 3.88 |
| 12 | Sam Houston State | 8 | 4 | 18 | 22 | 2.75 |