2025 Conference USA Leaders Rushing Defense - Games vs. Unranked Teams Only (AP Poll) through 12/13/2025
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Missouri State | 11 | 374 | 1689 | 4.52 | 19 | 34.00 | 153.55 |
| 2 | Louisiana Tech | 12 | 391 | 1704 | 4.36 | 13 | 32.58 | 142.00 |
| 3 | Middle Tennessee State | 12 | 440 | 1717 | 3.90 | 17 | 36.67 | 143.08 |
| 4 | UTEP | 11 | 440 | 1808 | 4.11 | 15 | 40.00 | 164.36 |
| 5 | FIU | 12 | 406 | 1915 | 4.72 | 16 | 33.83 | 159.58 |
| 6 | Liberty | 11 | 413 | 1922 | 4.65 | 20 | 37.55 | 174.73 |
| 7 | Jacksonville State | 13 | 474 | 1932 | 4.08 | 22 | 36.46 | 148.62 |
| 8 | Kennesaw State | 12 | 474 | 1968 | 4.15 | 20 | 39.50 | 164.00 |
| 9 | Delaware | 12 | 415 | 1972 | 4.75 | 25 | 34.58 | 164.33 |
| 10 | New Mexico State | 12 | 451 | 1980 | 4.39 | 14 | 37.58 | 165.00 |
| 11 | Western Kentucky | 12 | 430 | 2176 | 5.06 | 14 | 35.83 | 181.33 |
| 12 | Sam Houston State | 11 | 420 | 2227 | 5.30 | 29 | 38.18 | 202.45 |