2025 Conference USA Leaders Rushing Defense - Games at Home Only through 11/22/2025
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Jacksonville State | 4 | 140 | 542 | 3.87 | 6 | 35.00 | 135.50 |
| 2 | New Mexico State | 5 | 174 | 612 | 3.52 | 1 | 34.80 | 122.40 |
| 3 | Missouri State | 5 | 152 | 627 | 4.13 | 8 | 30.40 | 125.40 |
| 4 | Liberty | 5 | 162 | 679 | 4.19 | 7 | 32.40 | 135.80 |
| 5 | Delaware | 5 | 155 | 717 | 4.63 | 8 | 31.00 | 143.40 |
| 6 | Middle Tennessee State | 6 | 242 | 771 | 3.19 | 10 | 40.33 | 128.50 |
| 7 | Kennesaw State | 6 | 215 | 788 | 3.67 | 6 | 35.83 | 131.33 |
| 8 | Sam Houston State | 4 | 169 | 795 | 4.70 | 10 | 42.25 | 198.75 |
| 9 | Louisiana Tech | 6 | 211 | 966 | 4.58 | 6 | 35.17 | 161.00 |
| 10 | FIU | 6 | 220 | 1005 | 4.57 | 9 | 36.67 | 167.50 |
| 11 | Western Kentucky | 6 | 198 | 1006 | 5.08 | 5 | 33.00 | 167.67 |
| 12 | UTEP | 6 | 252 | 1050 | 4.17 | 7 | 42.00 | 175.00 |