2025 Conference USA Leaders Rushing Defense - Games vs. Ranked Teams Only (AP Poll) through 11/22/2025
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | New Mexico State | 1 | 39 | 194 | 4.97 | 4 | 39.00 | 194.00 |
| 2 | UTEP | 1 | 56 | 226 | 4.04 | 2 | 56.00 | 226.00 |
| 3 | Liberty | 1 | 42 | 227 | 5.40 | 3 | 42.00 | 227.00 |
| 4 | Sam Houston State | 1 | 41 | 264 | 6.44 | 4 | 41.00 | 264.00 |
| 5 | Kennesaw State | 1 | 39 | 313 | 8.03 | 3 | 39.00 | 313.00 |
| 6 | Missouri State | 2 | 64 | 400 | 6.25 | 9 | 32.00 | 200.00 |