2025 Conference USA Leaders Rushing Defense - Games vs. Unranked Teams Only (AP Poll) through 11/22/2025
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Missouri State | 9 | 289 | 1134 | 3.92 | 11 | 32.11 | 126.00 |
| 2 | Louisiana Tech | 11 | 364 | 1582 | 4.35 | 11 | 33.09 | 143.82 |
| 3 | FIU | 11 | 368 | 1719 | 4.67 | 15 | 33.45 | 156.27 |
| 4 | Western Kentucky | 11 | 382 | 1883 | 4.93 | 12 | 34.73 | 171.18 |
| 4 | Delaware | 11 | 382 | 1946 | 5.09 | 25 | 34.73 | 176.91 |
| 6 | Jacksonville State | 11 | 402 | 1656 | 4.12 | 17 | 36.55 | 150.55 |
| 7 | Liberty | 10 | 369 | 1710 | 4.63 | 17 | 36.90 | 171.00 |
| 8 | Middle Tennessee State | 11 | 413 | 1634 | 3.96 | 16 | 37.55 | 148.55 |
| 9 | Kennesaw State | 10 | 377 | 1467 | 3.89 | 13 | 37.70 | 146.70 |
| 10 | New Mexico State | 10 | 379 | 1587 | 4.19 | 9 | 37.90 | 158.70 |
| 11 | Sam Houston State | 10 | 380 | 1924 | 5.06 | 25 | 38.00 | 192.40 |
| 12 | UTEP | 10 | 403 | 1592 | 3.95 | 12 | 40.30 | 159.20 |