2025 Conference USA Leaders Rushing Defense - Games vs. FBS Teams With Winning Record Only through 11/01/2025
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Jacksonville State | 1 | 50 | 225 | 4.50 | 3 | 50.00 | 225.00 |
| 2 | Western Kentucky | 2 | 71 | 323 | 4.55 | 2 | 35.50 | 161.50 |
| 3 | Middle Tennessee State | 3 | 115 | 368 | 3.20 | 2 | 38.33 | 122.67 |
| 4 | UTEP | 3 | 137 | 471 | 3.44 | 5 | 45.67 | 157.00 |
| 5 | Louisiana Tech | 4 | 134 | 473 | 3.53 | 4 | 33.50 | 118.25 |
| 6 | Delaware | 3 | 108 | 538 | 4.98 | 7 | 36.00 | 179.33 |
| 7 | Missouri State | 3 | 93 | 559 | 6.01 | 11 | 31.00 | 186.33 |
| 8 | Kennesaw State | 4 | 154 | 671 | 4.36 | 6 | 38.50 | 167.75 |
| 9 | FIU | 4 | 134 | 686 | 5.12 | 8 | 33.50 | 171.50 |
| 10 | New Mexico State | 4 | 173 | 739 | 4.27 | 4 | 43.25 | 184.75 |
| 11 | Liberty | 3 | 137 | 783 | 5.72 | 7 | 45.67 | 261.00 |
| 12 | Sam Houston State | 6 | 245 | 1443 | 5.89 | 17 | 40.83 | 240.50 |