2025 Conference USA Leaders Rushing Defense - Games vs. FBS non-Power 5 Conference Teams Only through 12/13/2025
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 9 | 274 | 1293 | 4.72 | 9 | 30.44 | 143.67 |
| 2 | Delaware | 9 | 301 | 1379 | 4.58 | 19 | 33.44 | 153.22 |
| 3 | Middle Tennessee State | 10 | 362 | 1414 | 3.91 | 12 | 36.20 | 141.40 |
| 4 | Missouri State | 9 | 315 | 1451 | 4.61 | 15 | 35.00 | 161.22 |
| 5 | FIU | 10 | 345 | 1601 | 4.64 | 14 | 34.50 | 160.10 |
| 6 | New Mexico State | 10 | 377 | 1718 | 4.56 | 10 | 37.70 | 171.80 |
| 7 | Jacksonville State | 11 | 402 | 1732 | 4.31 | 22 | 36.55 | 157.45 |
| 7 | UTEP | 10 | 400 | 1732 | 4.33 | 14 | 40.00 | 173.20 |
| 9 | Kennesaw State | 10 | 389 | 1759 | 4.52 | 18 | 38.90 | 175.90 |
| 10 | Western Kentucky | 10 | 356 | 1897 | 5.33 | 14 | 35.60 | 189.70 |
| 11 | Liberty | 11 | 423 | 1965 | 4.65 | 22 | 38.45 | 178.64 |
| 12 | Sam Houston State | 10 | 380 | 2039 | 5.37 | 27 | 38.00 | 203.90 |