2025 Conference USA Leaders Rushing Defense - Games in August/September Only through 09/13/2025
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 3 | 95 | 281 | 2.96 | 1 | 31.67 | 93.67 |
| 2 | Sam Houston State | 3 | 102 | 383 | 3.75 | 4 | 34.00 | 127.67 |
| 3 | UTEP | 3 | 129 | 429 | 3.33 | 5 | 43.00 | 143.00 |
| 4 | FIU | 3 | 92 | 449 | 4.88 | 3 | 30.67 | 149.67 |
| 5 | Delaware | 3 | 112 | 505 | 4.51 | 6 | 37.33 | 168.33 |
| 6 | Middle Tennessee State | 3 | 113 | 506 | 4.48 | 5 | 37.67 | 168.67 |
| 7 | Kennesaw State | 3 | 124 | 522 | 4.21 | 5 | 41.33 | 174.00 |
| 8 | Jacksonville State | 3 | 116 | 526 | 4.53 | 4 | 38.67 | 175.33 |
| 9 | New Mexico State | 3 | 137 | 562 | 4.10 | 4 | 45.67 | 187.33 |
| 10 | Missouri State | 3 | 97 | 591 | 6.09 | 11 | 32.33 | 197.00 |
| 11 | Western Kentucky | 3 | 110 | 633 | 5.75 | 4 | 36.67 | 211.00 |
| 12 | Liberty | 3 | 118 | 680 | 5.76 | 6 | 39.33 | 226.67 |