2025 Conference USA Leaders Rushing Defense - Games vs. Unranked Teams Only (AP Poll) through 10/08/2025
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 4 | 125 | 400 | 3.20 | 0 | 31.25 | 100.00 |
| 2 | Kennesaw State | 4 | 150 | 456 | 3.04 | 5 | 37.50 | 114.00 |
| 3 | FIU | 5 | 156 | 739 | 4.74 | 6 | 31.20 | 147.80 |
| 4 | Sam Houston State | 5 | 174 | 742 | 4.26 | 10 | 34.80 | 148.40 |
| 5 | Missouri State | 6 | 176 | 907 | 5.15 | 14 | 29.33 | 151.17 |
| 6 | New Mexico State | 5 | 201 | 763 | 3.80 | 4 | 40.20 | 152.60 |
| 7 | Middle Tennessee State | 6 | 228 | 920 | 4.04 | 8 | 38.00 | 153.33 |
| 8 | Delaware | 5 | 172 | 773 | 4.49 | 8 | 34.40 | 154.60 |
| 9 | UTEP | 6 | 263 | 934 | 3.55 | 9 | 43.83 | 155.67 |
| 10 | Jacksonville State | 5 | 201 | 843 | 4.19 | 7 | 40.20 | 168.60 |
| 11 | Western Kentucky | 6 | 217 | 1175 | 5.41 | 9 | 36.17 | 195.83 |
| 12 | Liberty | 6 | 230 | 1181 | 5.13 | 10 | 38.33 | 196.83 |