2025 Conference USA Leaders Rushing Defense - Games in November Only through 12/13/2025
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Middle Tennessee State | 4 | 127 | 577 | 4.54 | 8 | 31.75 | 144.25 |
| 2 | FIU | 4 | 149 | 640 | 4.30 | 4 | 37.25 | 160.00 |
| 3 | Western Kentucky | 4 | 137 | 643 | 4.69 | 3 | 34.25 | 160.75 |
| 4 | Louisiana Tech | 4 | 134 | 657 | 4.90 | 7 | 33.50 | 164.25 |
| 5 | Jacksonville State | 4 | 160 | 749 | 4.68 | 9 | 40.00 | 187.25 |
| 6 | Sam Houston State | 4 | 151 | 778 | 5.15 | 11 | 37.75 | 194.50 |
| 7 | UTEP | 4 | 154 | 791 | 5.14 | 6 | 38.50 | 197.75 |
| 8 | Kennesaw State | 4 | 164 | 809 | 4.93 | 10 | 41.00 | 202.25 |
| 9 | Missouri State | 4 | 168 | 818 | 4.87 | 10 | 42.00 | 204.50 |
| 10 | Liberty | 5 | 187 | 822 | 4.40 | 12 | 37.40 | 164.40 |
| 11 | Delaware | 5 | 171 | 841 | 4.92 | 13 | 34.20 | 168.20 |
| 12 | New Mexico State | 5 | 188 | 977 | 5.20 | 8 | 37.60 | 195.40 |