2025 Conference USA Leaders Rushing Defense - From Opponent's 21 To 39 Yard Line through 11/22/2025
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Missouri State | 11 | 113 | 469 | 4.15 | 1 | 75 | 25 | 17 | 3 |
| 2 | New Mexico State | 11 | 131 | 530 | 4.05 | 0 | 32 | 31 | 17 | 3 |
| 3 | Jacksonville State | 11 | 109 | 541 | 4.96 | 0 | 45 | 28 | 18 | 7 |
| 4 | UTEP | 11 | 132 | 559 | 4.23 | 0 | 51 | 30 | 21 | 3 |
| 4 | Louisiana Tech | 11 | 118 | 559 | 4.74 | 0 | 36 | 32 | 20 | 4 |
| 6 | FIU | 11 | 114 | 623 | 5.46 | 1 | 67 | 36 | 24 | 7 |
| 7 | Sam Houston State | 11 | 107 | 627 | 5.86 | 1 | 67 | 28 | 22 | 7 |
| 8 | Liberty | 11 | 114 | 650 | 5.70 | 1 | 77 | 29 | 20 | 8 |
| 9 | Kennesaw State | 11 | 142 | 715 | 5.04 | 2 | 75 | 36 | 24 | 5 |
| 10 | Delaware | 11 | 123 | 725 | 5.89 | 2 | 72 | 29 | 18 | 10 |
| 11 | Middle Tennessee State | 11 | 124 | 758 | 6.11 | 1 | 66 | 35 | 20 | 9 |
| 12 | Western Kentucky | 11 | 127 | 789 | 6.21 | 1 | 75 | 31 | 22 | 10 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||