2021 American Athletic Conference Leaders Sacks - Games in October Only through 01/10/2022
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Houston | 4 | 19.0 | 121 | 4.75 |
| 2 | UCF | 5 | 16.0 | 95 | 3.20 |
| 3 | Cincinnati | 5 | 14.0 | 87 | 2.80 |
| 4 | East Carolina | 4 | 9.0 | 84 | 2.25 |
| 5 | Tulane | 4 | 8.0 | 53 | 2.00 |
| 5 | SMU | 4 | 8.0 | 51 | 2.00 |
| 7 | Tulsa | 4 | 6.0 | 32 | 1.50 |
| 8 | Memphis | 4 | 5.0 | 39 | 1.25 |
| 8 | Temple | 4 | 5.0 | 33 | 1.25 |
| 8 | Navy | 5 | 5.0 | 32 | 1.00 |
| 11 | South Florida | 4 | 2.0 | 10 | 0.50 |