2021 American Athletic Conference Leaders Sacks - Games Lost Only through 01/10/2022
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Tulane | 10 | 24.0 | 140 | 2.40 |
| 2 | East Carolina | 5 | 14.0 | 114 | 2.80 |
| 3 | Memphis | 6 | 11.0 | 63 | 1.83 |
| 4 | Navy | 8 | 8.0 | 54 | 1.00 |
| 5 | Temple | 9 | 7.0 | 54 | 0.78 |
| 5 | South Florida | 10 | 7.0 | 44 | 0.70 |
| 5 | Tulsa | 6 | 7.0 | 38 | 1.17 |
| 8 | SMU | 4 | 6.0 | 33 | 1.50 |
| 9 | Houston | 2 | 4.0 | 33 | 2.00 |
| 9 | UCF | 4 | 4.0 | 25 | 1.00 |
| 11 | Cincinnati | 1 | 2.0 | 8 | 2.00 |