2021 American Athletic Conference Leaders Sacks - Games at Home Only through 01/10/2022
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | UCF | 7 | 26.0 | 184 | 3.71 |
| 2 | Cincinnati | 7 | 23.0 | 126 | 3.29 |
| 3 | Memphis | 7 | 22.0 | 150 | 3.14 |
| 3 | Tulane | 6 | 22.0 | 148 | 3.67 |
| 5 | East Carolina | 6 | 15.0 | 99 | 2.50 |
| 6 | SMU | 6 | 14.0 | 94 | 2.33 |
| 6 | Houston | 5 | 14.0 | 79 | 2.80 |
| 8 | Tulsa | 6 | 12.0 | 57 | 2.00 |
| 9 | Temple | 6 | 11.0 | 78 | 1.83 |
| 10 | South Florida | 6 | 6.0 | 36 | 1.00 |
| 11 | Navy | 6 | 4.0 | 29 | 0.67 |