2025 Big 12 Conference Leaders Passes Defended - Games vs. FBS Power 5 Conference Teams Only through 08/29/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Kansas State | 1 | 0 | 6 | 6 | 6.00 |
| 2 | Iowa State | 1 | 0 | 4 | 4 | 4.00 |
| 3 | Baylor | 1 | 0 | 3 | 3 | 3.00 |
| 4 | Colorado | 1 | 1 | 2 | 3 | 3.00 |
| 4 | Cincinnati | 1 | 0 | 2 | 2 | 2.00 |