2025 Big 12 Conference Leaders Passes Defended - Games vs. FBS non-Power 5 Conference Teams Only through 11/08/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Colorado | 2 | 1 | 14 | 15 | 7.50 |
| 2 | Arizona | 1 | 3 | 5 | 8 | 8.00 |
| 2 | West Virginia | 1 | 3 | 5 | 8 | 8.00 |
| 2 | UCF | 1 | 1 | 5 | 6 | 6.00 |
| 2 | Arizona State | 1 | 0 | 5 | 5 | 5.00 |
| 6 | BYU | 1 | 2 | 4 | 6 | 6.00 |
| 6 | Kansas | 1 | 2 | 4 | 6 | 6.00 |
| 6 | Iowa State | 1 | 1 | 4 | 5 | 5.00 |
| 6 | Texas Tech | 1 | 1 | 4 | 5 | 5.00 |
| 6 | Oklahoma State | 1 | 0 | 4 | 4 | 4.00 |
| 11 | Utah | 1 | 1 | 2 | 3 | 3.00 |
| 12 | Houston | 1 | 1 | 1 | 2 | 2.00 |
| 12 | Cincinnati | 1 | 0 | 1 | 1 | 1.00 |