2025 Big 12 Conference Leaders Passes Defended - Games Won Only through 10/17/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Texas Tech | 6 | 8 | 25 | 33 | 5.50 |
| 2 | Arizona | 4 | 6 | 22 | 28 | 7.00 |
| 3 | Houston | 5 | 6 | 20 | 26 | 5.20 |
| 4 | Arizona State | 4 | 4 | 19 | 23 | 5.75 |
| 5 | Iowa State | 5 | 6 | 18 | 24 | 4.80 |
| 5 | Cincinnati | 5 | 0 | 18 | 18 | 3.60 |
| 7 | BYU | 6 | 8 | 17 | 25 | 4.17 |
| 7 | Kansas | 4 | 3 | 17 | 20 | 5.00 |
| 9 | Utah | 5 | 4 | 16 | 20 | 4.00 |
| 10 | Baylor | 4 | 5 | 15 | 20 | 5.00 |
| 10 | Kansas State | 3 | 4 | 15 | 19 | 6.33 |
| 10 | Colorado | 3 | 2 | 15 | 17 | 5.67 |
| 13 | TCU | 4 | 6 | 12 | 18 | 4.50 |
| 13 | UCF | 3 | 4 | 12 | 16 | 5.33 |
| 15 | West Virginia | 2 | 1 | 5 | 6 | 3.00 |
| 16 | Oklahoma State | 1 | 1 | 2 | 3 | 3.00 |