2025 Big 12 Conference Leaders Passes Defended - Games Lost Only through 11/08/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Oklahoma State | 8 | 2 | 25 | 27 | 3.38 |
| 2 | Colorado | 7 | 3 | 23 | 26 | 3.71 |
| 3 | Kansas | 5 | 1 | 21 | 22 | 4.40 |
| 4 | West Virginia | 6 | 7 | 18 | 25 | 4.17 |
| 5 | Kansas State | 5 | 3 | 16 | 19 | 3.80 |
| 6 | Iowa State | 4 | 1 | 13 | 14 | 3.50 |
| 7 | UCF | 5 | 4 | 11 | 15 | 3.00 |
| 7 | Arizona | 3 | 3 | 11 | 14 | 4.67 |
| 7 | Baylor | 4 | 0 | 11 | 11 | 2.75 |
| 10 | Cincinnati | 2 | 1 | 10 | 11 | 5.50 |
| 11 | TCU | 3 | 2 | 9 | 11 | 3.67 |
| 11 | Arizona State | 3 | 0 | 9 | 9 | 3.00 |
| 13 | Texas Tech | 1 | 0 | 7 | 7 | 7.00 |
| 14 | Utah | 2 | 2 | 6 | 8 | 4.00 |
| 15 | BYU | 1 | 0 | 5 | 5 | 5.00 |
| 15 | Houston | 2 | 0 | 5 | 5 | 2.50 |