2025 Conference USA Leaders Passes Defended - Games vs. FBS (I-A) Teams Only through 11/01/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 7 | 11 | 45 | 56 | 8.00 |
| 2 | Missouri State | 7 | 6 | 31 | 37 | 5.29 |
| 3 | New Mexico State | 7 | 9 | 27 | 36 | 5.14 |
| 3 | Kennesaw State | 7 | 3 | 33 | 36 | 5.14 |
| 5 | Western Kentucky | 8 | 7 | 33 | 40 | 5.00 |
| 5 | FIU | 7 | 7 | 28 | 35 | 5.00 |
| 7 | Liberty | 7 | 5 | 24 | 29 | 4.14 |
| 7 | UTEP | 7 | 3 | 26 | 29 | 4.14 |
| 9 | Jacksonville State | 7 | 2 | 23 | 25 | 3.57 |
| 10 | Middle Tennessee State | 7 | 4 | 20 | 24 | 3.43 |
| 11 | Delaware | 7 | 3 | 20 | 23 | 3.29 |
| 12 | Sam Houston State | 8 | 4 | 18 | 22 | 2.75 |