2025 Conference USA Leaders Passes Defended - Games Lost Only through 11/22/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | New Mexico State | 7 | 10 | 24 | 34 | 4.86 |
| 2 | FIU | 5 | 1 | 21 | 22 | 4.40 |
| 3 | Middle Tennessee State | 9 | 5 | 31 | 36 | 4.00 |
| 3 | Louisiana Tech | 5 | 4 | 16 | 20 | 4.00 |
| 3 | Jacksonville State | 4 | 2 | 14 | 16 | 4.00 |
| 6 | UTEP | 9 | 5 | 30 | 35 | 3.89 |
| 7 | Western Kentucky | 3 | 2 | 9 | 11 | 3.67 |
| 8 | Liberty | 7 | 3 | 21 | 24 | 3.43 |
| 9 | Missouri State | 4 | 1 | 12 | 13 | 3.25 |
| 10 | Sam Houston State | 9 | 4 | 22 | 26 | 2.89 |
| 11 | Delaware | 6 | 2 | 12 | 14 | 2.33 |
| 11 | Kennesaw State | 3 | 0 | 7 | 7 | 2.33 |