2025 Conference USA Leaders Passes Defended - Games vs. FBS (I-A) Teams Only through 10/08/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 4 | 9 | 29 | 38 | 9.50 |
| 2 | Western Kentucky | 5 | 5 | 18 | 23 | 4.60 |
| 3 | FIU | 4 | 4 | 18 | 22 | 5.50 |
| 3 | Missouri State | 5 | 2 | 20 | 22 | 4.40 |
| 5 | UTEP | 5 | 2 | 18 | 20 | 4.00 |
| 6 | Kennesaw State | 4 | 1 | 17 | 18 | 4.50 |
| 6 | Liberty | 5 | 4 | 14 | 18 | 3.60 |
| 6 | Middle Tennessee State | 5 | 3 | 15 | 18 | 3.60 |
| 6 | Sam Houston State | 5 | 2 | 16 | 18 | 3.60 |
| 10 | New Mexico State | 4 | 4 | 12 | 16 | 4.00 |
| 11 | Delaware | 4 | 2 | 12 | 14 | 3.50 |
| 11 | Jacksonville State | 4 | 1 | 13 | 14 | 3.50 |