2025 Conference USA Leaders Passes Defended - Games vs. FBS Teams With Non-Winning Record Only through 12/13/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 6 | 14 | 32 | 46 | 7.67 |
| 2 | Western Kentucky | 5 | 5 | 29 | 34 | 6.80 |
| 3 | Missouri State | 5 | 6 | 27 | 33 | 6.60 |
| 4 | FIU | 6 | 9 | 30 | 39 | 6.50 |
| 5 | New Mexico State | 5 | 6 | 22 | 28 | 5.60 |
| 6 | Liberty | 4 | 3 | 18 | 21 | 5.25 |
| 7 | Kennesaw State | 5 | 3 | 23 | 26 | 5.20 |
| 8 | Delaware | 5 | 6 | 17 | 23 | 4.60 |
| 9 | Middle Tennessee State | 6 | 7 | 17 | 24 | 4.00 |
| 10 | Sam Houston State | 5 | 4 | 14 | 18 | 3.60 |
| 11 | UTEP | 6 | 1 | 19 | 20 | 3.33 |
| 12 | Jacksonville State | 7 | 3 | 20 | 23 | 3.29 |