2025 Conference USA Leaders Passes Defended - Games in October Only through 12/13/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Missouri State | 3 | 4 | 17 | 21 | 7.00 |
| 2 | New Mexico State | 3 | 5 | 15 | 20 | 6.67 |
| 3 | Louisiana Tech | 3 | 2 | 16 | 18 | 6.00 |
| 3 | Kennesaw State | 3 | 2 | 16 | 18 | 6.00 |
| 5 | Liberty | 2 | 2 | 9 | 11 | 5.50 |
| 6 | Middle Tennessee State | 3 | 1 | 13 | 14 | 4.67 |
| 7 | UTEP | 3 | 1 | 12 | 13 | 4.33 |
| 8 | FIU | 4 | 3 | 13 | 16 | 4.00 |
| 9 | Jacksonville State | 3 | 1 | 10 | 11 | 3.67 |
| 10 | Western Kentucky | 3 | 2 | 8 | 10 | 3.33 |
| 10 | Delaware | 3 | 1 | 9 | 10 | 3.33 |
| 12 | Sam Houston State | 4 | 2 | 4 | 6 | 1.50 |