2025 Conference USA Leaders Passes Defended - Games vs. FBS Teams With Winning Record Only through 10/08/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 3 | 4 | 20 | 24 | 8.00 |
| 2 | FIU | 3 | 1 | 14 | 15 | 5.00 |
| 3 | UTEP | 4 | 2 | 14 | 16 | 4.00 |
| 3 | Western Kentucky | 2 | 2 | 6 | 8 | 4.00 |
| 5 | Sam Houston State | 5 | 2 | 16 | 18 | 3.60 |
| 6 | Liberty | 2 | 2 | 5 | 7 | 3.50 |
| 7 | Missouri State | 3 | 1 | 9 | 10 | 3.33 |
| 8 | Jacksonville State | 2 | 0 | 6 | 6 | 3.00 |
| 9 | Delaware | 2 | 0 | 5 | 5 | 2.50 |
| 9 | Kennesaw State | 2 | 0 | 5 | 5 | 2.50 |
| 11 | New Mexico State | 2 | 1 | 3 | 4 | 2.00 |
| 12 | Middle Tennessee State | 1 | 0 | 1 | 1 | 1.00 |