2022 Conference USA Leaders Passes Defended - Games Lost Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Middle Tennessee | 5 | 5 | 28 | 33 | 6.60 |
| 2 | Florida Atlantic | 7 | 6 | 25 | 31 | 4.43 |
| 3 | Louisiana Tech | 9 | 4 | 32 | 36 | 4.00 |
| 4 | UAB | 6 | 0 | 22 | 22 | 3.67 |
| 4 | UTSA | 3 | 2 | 9 | 11 | 3.67 |
| 6 | Western Kentucky | 5 | 1 | 16 | 17 | 3.40 |
| 7 | UTEP | 7 | 2 | 18 | 20 | 2.86 |
| 8 | Rice | 8 | 3 | 18 | 21 | 2.63 |
| 9 | Florida International | 8 | 4 | 16 | 20 | 2.50 |
| 10 | North Texas | 7 | 2 | 12 | 14 | 2.00 |
| 11 | Charlotte | 9 | 5 | 9 | 14 | 1.56 |