2025 Conference USA Leaders Passes Defended - Games vs. FBS Teams With Winning Record Only through 11/01/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 4 | 3 | 20 | 23 | 5.75 |
| 2 | Kennesaw State | 4 | 2 | 19 | 21 | 5.25 |
| 3 | New Mexico State | 4 | 4 | 16 | 20 | 5.00 |
| 4 | Sam Houston State | 6 | 3 | 15 | 18 | 3.00 |
| 5 | UTEP | 3 | 3 | 14 | 17 | 5.67 |
| 6 | FIU | 4 | 3 | 13 | 16 | 4.00 |
| 7 | Middle Tennessee State | 3 | 0 | 11 | 11 | 3.67 |
| 8 | Missouri State | 3 | 1 | 9 | 10 | 3.33 |
| 9 | Western Kentucky | 2 | 1 | 7 | 8 | 4.00 |
| 9 | Liberty | 3 | 2 | 6 | 8 | 2.67 |
| 11 | Delaware | 3 | 0 | 5 | 5 | 1.67 |
| 12 | Jacksonville State | 1 | 0 | 4 | 4 | 4.00 |