2025 Conference USA Leaders Passes Defended - Games vs. Conference Teams Only through 11/01/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 5 | 9 | 32 | 41 | 8.20 |
| 2 | New Mexico State | 5 | 7 | 20 | 27 | 5.40 |
| 3 | Western Kentucky | 6 | 4 | 28 | 32 | 5.33 |
| 3 | Missouri State | 4 | 4 | 21 | 25 | 6.25 |
| 3 | FIU | 4 | 4 | 15 | 19 | 4.75 |
| 6 | Kennesaw State | 4 | 3 | 20 | 23 | 5.75 |
| 6 | Liberty | 4 | 3 | 14 | 17 | 4.25 |
| 6 | Delaware | 5 | 3 | 14 | 17 | 3.40 |
| 9 | UTEP | 4 | 2 | 17 | 19 | 4.75 |
| 9 | Jacksonville State | 4 | 2 | 15 | 17 | 4.25 |
| 9 | Sam Houston State | 5 | 2 | 9 | 11 | 2.20 |
| 12 | Middle Tennessee State | 4 | 1 | 13 | 14 | 3.50 |