2025 Conference USA Leaders Passes Defended - Games vs. Conference Teams Only through 11/22/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 7 | 15 | 38 | 53 | 7.57 |
| 2 | New Mexico State | 7 | 10 | 30 | 40 | 5.71 |
| 3 | Jacksonville State | 7 | 9 | 27 | 36 | 5.14 |
| 4 | FIU | 7 | 7 | 34 | 41 | 5.86 |
| 4 | Kennesaw State | 7 | 7 | 30 | 37 | 5.29 |
| 6 | Missouri State | 7 | 5 | 35 | 40 | 5.71 |
| 6 | Middle Tennessee State | 7 | 5 | 27 | 32 | 4.57 |
| 8 | Western Kentucky | 7 | 4 | 35 | 39 | 5.57 |
| 8 | Liberty | 7 | 4 | 24 | 28 | 4.00 |
| 8 | UTEP | 7 | 4 | 23 | 27 | 3.86 |
| 8 | Delaware | 7 | 4 | 20 | 24 | 3.43 |
| 12 | Sam Houston State | 7 | 3 | 16 | 19 | 2.71 |