2025 Conference USA Leaders Rushing Defense - Games vs. FBS non-Power 5 Conference Teams Only through 09/13/2025
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 1 | 17 | 27 | 1.59 | 0 | 17.00 | 27.00 |
| 2 | Sam Houston State | 3 | 102 | 383 | 3.75 | 4 | 34.00 | 127.67 |
| 3 | UTEP | 1 | 33 | 127 | 3.85 | 2 | 33.00 | 127.00 |
| 4 | FIU | 1 | 31 | 135 | 4.35 | 1 | 31.00 | 135.00 |
| 5 | New Mexico State | 2 | 102 | 494 | 4.84 | 4 | 51.00 | 247.00 |
| 6 | Jacksonville State | 2 | 79 | 418 | 5.29 | 4 | 39.50 | 209.00 |
| 7 | Delaware | 1 | 32 | 175 | 5.47 | 3 | 32.00 | 175.00 |
| 8 | Liberty | 2 | 86 | 496 | 5.77 | 5 | 43.00 | 248.00 |
| 9 | Missouri State | 1 | 33 | 191 | 5.79 | 2 | 33.00 | 191.00 |
| 10 | Middle Tennessee State | 1 | 35 | 203 | 5.80 | 0 | 35.00 | 203.00 |
| 11 | Western Kentucky | 2 | 73 | 480 | 6.58 | 4 | 36.50 | 240.00 |