2025 Conference USA Leaders Total Defense - Games vs. FBS Teams With Winning Record Only through 11/12/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Jacksonville State | 2 | 259 | 574 | 144 | 833 | 5.78 | 416.5 |
| 2 | Missouri State | 3 | 559 | 962 | 195 | 1521 | 7.80 | 507.0 |
| 3 | Kennesaw State | 3 | 579 | 667 | 217 | 1246 | 5.74 | 415.3 |
| 4 | Delaware | 4 | 669 | 911 | 261 | 1580 | 6.05 | 395.0 |
| 5 | Middle Tennessee State | 4 | 447 | 951 | 267 | 1398 | 5.24 | 349.5 |
| 6 | Western Kentucky | 4 | 751 | 1055 | 292 | 1806 | 6.18 | 451.5 |
| 7 | FIU | 5 | 826 | 1260 | 319 | 2086 | 6.54 | 417.2 |
| 8 | Liberty | 5 | 905 | 1166 | 332 | 2071 | 6.24 | 414.2 |
| 9 | UTEP | 5 | 873 | 819 | 351 | 1692 | 4.82 | 338.4 |
| 10 | Louisiana Tech | 5 | 568 | 1450 | 368 | 2018 | 5.48 | 403.6 |
| 11 | New Mexico State | 5 | 947 | 1368 | 383 | 2315 | 6.04 | 463.0 |
| 12 | Sam Houston State | 6 | 1443 | 1637 | 428 | 3080 | 7.20 | 513.3 |