2025 Conference USA Leaders Total Defense - Games Lost Only through 11/12/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Western Kentucky | 2 | 556 | 405 | 133 | 961 | 7.23 | 480.5 |
| 2 | Kennesaw State | 2 | 443 | 498 | 142 | 941 | 6.63 | 470.5 |
| 3 | Missouri State | 3 | 559 | 962 | 195 | 1521 | 7.80 | 507.0 |
| 4 | Jacksonville State | 3 | 552 | 657 | 208 | 1209 | 5.81 | 403.0 |
| 5 | Delaware | 4 | 775 | 910 | 265 | 1685 | 6.36 | 421.3 |
| 6 | Louisiana Tech | 4 | 446 | 1058 | 286 | 1504 | 5.26 | 376.0 |
| 7 | FIU | 5 | 919 | 1235 | 319 | 2154 | 6.75 | 430.8 |
| 8 | Liberty | 5 | 987 | 968 | 325 | 1955 | 6.02 | 391.0 |
| 9 | New Mexico State | 6 | 1061 | 1547 | 443 | 2608 | 5.89 | 434.7 |
| 10 | UTEP | 7 | 1283 | 1211 | 491 | 2494 | 5.08 | 356.3 |
| 11 | Middle Tennessee State | 8 | 1081 | 1945 | 536 | 3026 | 5.65 | 378.3 |
| 12 | Sam Houston State | 8 | 1713 | 2128 | 545 | 3841 | 7.05 | 480.1 |