2025 Conference USA Leaders Total Defense - Games vs. FBS Teams With Winning Record Only through 10/08/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | UTEP | 4 | 698 | 633 | 267 | 1331 | 4.99 | 332.8 |
| 2 | Jacksonville State | 2 | 333 | 466 | 142 | 799 | 5.63 | 399.5 |
| 3 | Louisiana Tech | 3 | 276 | 912 | 207 | 1188 | 5.74 | 396.0 |
| 4 | FIU | 3 | 499 | 788 | 197 | 1287 | 6.53 | 429.0 |
| 5 | Middle Tennessee State | 1 | 157 | 177 | 51 | 334 | 6.55 | 334.0 |
| 6 | Western Kentucky | 2 | 428 | 515 | 143 | 943 | 6.59 | 471.5 |
| 7 | Sam Houston State | 5 | 742 | 1542 | 345 | 2284 | 6.62 | 456.8 |
| 8 | Kennesaw State | 2 | 443 | 498 | 142 | 941 | 6.63 | 470.5 |
| 9 | Delaware | 2 | 283 | 576 | 128 | 859 | 6.71 | 429.5 |
| 10 | Liberty | 2 | 445 | 484 | 138 | 929 | 6.73 | 464.5 |
| 11 | New Mexico State | 2 | 485 | 565 | 154 | 1050 | 6.82 | 525.0 |
| 12 | Missouri State | 3 | 559 | 962 | 195 | 1521 | 7.80 | 507.0 |