2025 Conference USA Leaders Total Defense - Games vs. FBS (I-A) Teams Only through 12/13/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Missouri State | 11 | 1851 | 2545 | 729 | 4396 | 6.03 | 399.6 |
| 2 | Delaware | 11 | 1772 | 2813 | 738 | 4585 | 6.21 | 416.8 |
| 3 | Middle Tennessee State | 11 | 1567 | 2881 | 740 | 4448 | 6.01 | 404.4 |
| 4 | Liberty | 11 | 1965 | 2229 | 742 | 4194 | 5.65 | 381.3 |
| 5 | Louisiana Tech | 11 | 1578 | 2668 | 751 | 4246 | 5.65 | 386.0 |
| 6 | FIU | 11 | 1810 | 2713 | 764 | 4523 | 5.92 | 411.2 |
| 7 | Western Kentucky | 11 | 2023 | 2552 | 776 | 4575 | 5.90 | 415.9 |
| 8 | New Mexico State | 11 | 1912 | 2655 | 791 | 4567 | 5.77 | 415.2 |
| 9 | UTEP | 11 | 1958 | 2367 | 800 | 4325 | 5.41 | 393.2 |
| 10 | Jacksonville State | 12 | 1840 | 3013 | 822 | 4853 | 5.90 | 404.4 |
| 11 | Sam Houston State | 12 | 2491 | 3311 | 832 | 5802 | 6.97 | 483.5 |
| 12 | Kennesaw State | 12 | 2202 | 2746 | 852 | 4948 | 5.81 | 412.3 |