2025 Conference USA Leaders Total Defense - Games vs. FBS (I-A) Teams Only through 11/12/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Middle Tennessee State | 8 | 1134 | 1918 | 522 | 3052 | 5.85 | 381.5 |
| 2 | Liberty | 8 | 1265 | 1665 | 527 | 2930 | 5.56 | 366.3 |
| 3 | Missouri State | 8 | 1235 | 1946 | 528 | 3181 | 6.02 | 397.6 |
| 4 | Jacksonville State | 8 | 1145 | 2029 | 534 | 3174 | 5.94 | 396.8 |
| 5 | Delaware | 8 | 1344 | 1942 | 536 | 3286 | 6.13 | 410.8 |
| 6 | FIU | 8 | 1203 | 2134 | 543 | 3337 | 6.15 | 417.1 |
| 7 | Western Kentucky | 8 | 1446 | 1745 | 561 | 3191 | 5.69 | 398.9 |
| 8 | Louisiana Tech | 8 | 1016 | 2087 | 564 | 3103 | 5.50 | 387.9 |
| 9 | UTEP | 8 | 1442 | 1450 | 567 | 2892 | 5.10 | 361.5 |
| 10 | New Mexico State | 8 | 1271 | 2025 | 585 | 3296 | 5.63 | 412.0 |
| 11 | Kennesaw State | 8 | 1258 | 1895 | 593 | 3153 | 5.32 | 394.1 |
| 12 | Sam Houston State | 9 | 1901 | 2414 | 627 | 4315 | 6.88 | 479.4 |