2025 Conference USA Leaders Total Defense - Games vs. Unranked Teams Only (AP Poll) through 09/13/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 2 | 153 | 426 | 125 | 579 | 4.63 | 289.5 |
| 2 | Missouri State | 2 | 358 | 364 | 127 | 722 | 5.69 | 361.0 |
| 3 | UTEP | 2 | 203 | 528 | 137 | 731 | 5.34 | 365.5 |
| 4 | Kennesaw State | 2 | 209 | 433 | 138 | 642 | 4.65 | 321.0 |
| 5 | FIU | 2 | 240 | 584 | 151 | 824 | 5.46 | 412.0 |
| 6 | Middle Tennessee State | 3 | 506 | 642 | 192 | 1148 | 5.98 | 382.7 |
| 7 | Liberty | 3 | 680 | 330 | 193 | 1010 | 5.23 | 336.7 |
| 8 | Western Kentucky | 3 | 633 | 515 | 196 | 1148 | 5.86 | 382.7 |
| 9 | Jacksonville State | 3 | 526 | 840 | 202 | 1366 | 6.76 | 455.3 |
| 10 | Delaware | 3 | 505 | 763 | 208 | 1268 | 6.10 | 422.7 |
| 11 | Sam Houston State | 3 | 383 | 944 | 219 | 1327 | 6.06 | 442.3 |
| 12 | New Mexico State | 3 | 562 | 642 | 230 | 1204 | 5.23 | 401.3 |