2025 Conference USA Leaders Total Defense - All Games through 11/12/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Missouri State | 9 | 1306 | 2096 | 585 | 3402 | 5.82 | 378.0 |
| 2 | Liberty | 9 | 1449 | 1797 | 590 | 3246 | 5.50 | 360.7 |
| 3 | Middle Tennessee State | 9 | 1284 | 2111 | 596 | 3395 | 5.70 | 377.2 |
| 4 | Jacksonville State | 9 | 1237 | 2170 | 602 | 3407 | 5.66 | 378.6 |
| 5 | Delaware | 9 | 1544 | 2091 | 603 | 3635 | 6.03 | 403.9 |
| 6 | FIU | 9 | 1308 | 2375 | 612 | 3683 | 6.02 | 409.2 |
| 7 | Sam Houston State | 9 | 1901 | 2414 | 627 | 4315 | 6.88 | 479.4 |
| 8 | Western Kentucky | 9 | 1599 | 1850 | 633 | 3449 | 5.45 | 383.2 |
| 9 | Louisiana Tech | 9 | 1142 | 2232 | 639 | 3374 | 5.28 | 374.9 |
| 10 | UTEP | 9 | 1518 | 1745 | 643 | 3263 | 5.07 | 362.6 |
| 11 | New Mexico State | 9 | 1339 | 2212 | 653 | 3551 | 5.44 | 394.6 |
| 12 | Kennesaw State | 9 | 1337 | 2110 | 656 | 3447 | 5.25 | 383.0 |