2025 Conference USA Leaders Total Defense - Games vs. Conference Teams Only through 11/12/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Liberty | 5 | 662 | 1035 | 321 | 1697 | 5.29 | 339.4 |
| 2 | Jacksonville State | 5 | 593 | 1372 | 326 | 1965 | 6.03 | 393.0 |
| 3 | FIU | 5 | 709 | 1214 | 330 | 1923 | 5.83 | 384.6 |
| 4 | Middle Tennessee State | 5 | 591 | 1208 | 333 | 1799 | 5.40 | 359.8 |
| 5 | Sam Houston State | 5 | 1171 | 1242 | 343 | 2413 | 7.03 | 482.6 |
| 6 | Missouri State | 5 | 644 | 1218 | 344 | 1862 | 5.41 | 372.4 |
| 7 | UTEP | 5 | 839 | 954 | 368 | 1793 | 4.87 | 358.6 |
| 8 | Kennesaw State | 5 | 723 | 1171 | 382 | 1894 | 4.96 | 378.8 |
| 9 | Delaware | 6 | 1039 | 1328 | 395 | 2367 | 5.99 | 394.5 |
| 10 | Louisiana Tech | 6 | 766 | 1458 | 407 | 2224 | 5.46 | 370.7 |
| 11 | Western Kentucky | 6 | 932 | 1379 | 426 | 2311 | 5.42 | 385.2 |
| 12 | New Mexico State | 6 | 998 | 1447 | 439 | 2445 | 5.57 | 407.5 |