2025 Atlantic Coast Conference Leaders Passes Defended - Games on the Road/Neutral Site Only through 11/22/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Virginia | 5 | 5 | 26 | 31 | 6.20 |
| 2 | SMU | 5 | 8 | 24 | 32 | 6.40 |
| 3 | California | 6 | 5 | 21 | 26 | 4.33 |
| 4 | Syracuse | 6 | 2 | 18 | 20 | 3.33 |
| 5 | NC State | 5 | 4 | 17 | 21 | 4.20 |
| 6 | Pittsburgh | 5 | 10 | 15 | 25 | 5.00 |
| 6 | Louisville | 4 | 7 | 15 | 22 | 5.50 |
| 6 | Duke | 6 | 5 | 15 | 20 | 3.33 |
| 6 | Wake Forest | 4 | 2 | 15 | 17 | 4.25 |
| 10 | Miami (FL) | 3 | 2 | 14 | 16 | 5.33 |
| 10 | North Carolina | 5 | 2 | 14 | 16 | 3.20 |
| 10 | Georgia Tech | 5 | 0 | 14 | 14 | 2.80 |
| 13 | Boston College | 4 | 1 | 11 | 12 | 3.00 |
| 14 | Stanford | 6 | 0 | 10 | 10 | 1.67 |
| 15 | Clemson | 4 | 1 | 9 | 10 | 2.50 |
| 16 | Florida State | 4 | 4 | 8 | 12 | 3.00 |
| 17 | Virginia Tech | 4 | 0 | 7 | 7 | 1.75 |