2025 Atlantic Coast Conference Leaders Passes Defended - Games vs. FBS Teams With Winning Record Only through 11/22/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Virginia | 6 | 4 | 40 | 44 | 7.33 |
| 2 | California | 5 | 2 | 30 | 32 | 6.40 |
| 3 | SMU | 6 | 9 | 27 | 36 | 6.00 |
| 3 | Miami (FL) | 5 | 4 | 27 | 31 | 6.20 |
| 3 | Syracuse | 9 | 3 | 27 | 30 | 3.33 |
| 6 | Boston College | 8 | 5 | 26 | 31 | 3.88 |
| 7 | Louisville | 7 | 8 | 25 | 33 | 4.71 |
| 8 | NC State | 8 | 6 | 23 | 29 | 3.63 |
| 9 | Clemson | 6 | 4 | 22 | 26 | 4.33 |
| 9 | Virginia Tech | 8 | 3 | 22 | 25 | 3.13 |
| 9 | Stanford | 7 | 2 | 22 | 24 | 3.43 |
| 12 | North Carolina | 6 | 2 | 21 | 23 | 3.83 |
| 13 | Duke | 8 | 9 | 20 | 29 | 3.63 |
| 14 | Wake Forest | 5 | 1 | 19 | 20 | 4.00 |
| 15 | Pittsburgh | 5 | 5 | 17 | 22 | 4.40 |
| 16 | Florida State | 7 | 6 | 14 | 20 | 2.86 |
| 16 | Georgia Tech | 5 | 1 | 14 | 15 | 3.00 |