2025 Atlantic Coast Conference Leaders Passes Defended - Games vs. FBS Power 5 Conference Teams Only through 09/19/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | California | 2 | 2 | 11 | 13 | 6.50 |
| 2 | SMU | 1 | 0 | 7 | 7 | 7.00 |
| 3 | Clemson | 2 | 0 | 6 | 6 | 3.00 |
| 4 | NC State | 2 | 3 | 5 | 8 | 4.00 |
| 4 | Georgia Tech | 2 | 1 | 5 | 6 | 3.00 |
| 4 | Florida State | 1 | 0 | 5 | 5 | 5.00 |
| 7 | Virginia Tech | 2 | 1 | 4 | 5 | 2.50 |
| 7 | Duke | 1 | 0 | 4 | 4 | 4.00 |
| 7 | Syracuse | 1 | 0 | 4 | 4 | 4.00 |
| 7 | Wake Forest | 1 | 0 | 4 | 4 | 4.00 |
| 11 | Pittsburgh | 1 | 2 | 3 | 5 | 5.00 |
| 11 | Stanford | 2 | 1 | 3 | 4 | 2.00 |
| 11 | Virginia | 1 | 0 | 3 | 3 | 3.00 |
| 11 | Boston College | 2 | 0 | 3 | 3 | 1.50 |
| 15 | North Carolina | 1 | 1 | 2 | 3 | 3.00 |